Role of Combinatorial, Medicinal & Biological Chemistry in Drug Discovery Development: An Introduction (AOICS) - Lupine Publishers
Combinatorial chemistry, a new approach for greatly reducing the time
for the discovery of newer organic motifs, has been developed over the
last few years. Combinatorial chemistry (Figure 1) is a technique for
creating huge numbers of biologically potent motif and their hybrids,
then rapidly screening them for desirable properties 1. Almost
pharmaceutical and agrochemical industries uses this strategy because of
the potential for immense reducing in time and cost, and several drug
candidates presently in clinical trials are products of this
methodology. Drug discovery process (Figure 2 & 3) is long, time and
money intensive process [1].
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