Lupine Publishers|Palauamine and Olympiadane Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations

Lupine Publishers|chemistry journals

Editorial

In the current editorial, we study Palau’amine and Olympiadane Nano molecules (Figures 1 & 2) incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. In this regard, the development of Chemical Modified Electrodes (CEMs) is at present an area of great interest. CEMs can be divided broadly into two main categories; namely, surface modified and bulk modified electrodes. Methods of surface modification include adsorption, covalent bonding, attachment of polymer Nano films, etc. Polymer Nano film coated electrodes can be differentiated from other modification methods such as adsorption and covalent bonding in that they usually involve multilayer as opposed to monolayer frequently encountered for the latter methods. The thicker Nano films imply more active sites which lead to larger analytical signals. This advantage coupled with other, their versatility and wide applicability, makes polymer Nano film modified electrodes particularly suitable for analytical applications [1–27].

Figure 1: Molecular structure of Palau’amine Nano molecules.

Figure 2: Molecular structure of Olympiadane Nano molecules.
Electrochemical polymerization offers the advantage of reproducible deposition in terms of Nano film thickness and loading, making the immobilization procedure of a metal–based electro catalyst very simple and reliable for Palau’ amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. Also, it must be notice that the nature of working electrode substrate in electro preparation of polymeric Nano film is very important, because properties of polymeric Nano films depend on the working electrode anti–cancer Nano materials. The ease and fast preparation and of obtaining a new reproducible surface, the low residual current, porous surface and low cost of Multi–Walled Carbon Nanotubes (MWCNTs) paste are some advantages of Carbon Paste Electrode (CPE) over all other solid electrodes [28–92].
On the other hand, it has been shown that, macrocyclic complexes of Palau’amine and Olympiadane Nano molecules– encapsulating Carbon nanotubes are interest as modifying agents because in basic media Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes redox centers show high catalytic activity towards the oxidation of small organic anti-cancer Nano compounds. The high–valence species of Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes seem to act as strong oxidizing agents for low-electroactivity organic substrates. 1,2–Dioxetane (1,2– Dioxacyclobutane), 1,3–Dioxetane (1,3– Dioxacyclobutane), DMDM Hydantoin and Sulphobe as the anti–cancer organic intermediate products of methanol oxidation as well as formic acid, is important to investigate its electrochemical oxidation behavior in Palau’ amine and Olympiadane Nano molecules-encapsulating Carbon nanotubes incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations [93–110].
In this editorial, we decided to combine the above mentioned advantageous features for the aim of Palau’ amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. Furthermore, in this editorial, we prepared poly Nano films by electropolymerization at the surface of Multi-Walled Carbon Nanotubes (MWCNTs) paste electrode. Then, Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes were incorporated into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) in a solution. The modifier layer of Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes at the electrode surface acts as a Nano catalyst for the treatment of human cancer cells, tissues and tumors under synchrotron and synchrocyclotron radiations. Suitability of this Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes–modified polymeric Multi–Walled Carbon Nano tubes (MWCNTs) paste electrode toward the electrocatalytic treatment of human cancer cells, tissues and tumors under synchrotron and synchrocyclotron radiations in alkaline medium at ambient temperature was investigated [111– 153].

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Chemical Sciences Journal- Lupine Publishers

Air Quality in Welding Workshops and Its Health Implication on Welders in Port Harcourt by Chukwu Okeah GO in Archives of Organic and Inorganic Chemical Sciences in Lupine Publishers

The study was carried out in Port Harcourt to ascertain the air quality status of air in welding workshops and the health implication on welders in Port Harcourt. Five objectives alongside five research questions were set to guide in the achievement of the aim of the study. The experimental and the cross sectional research design were adopted in carrying out this study. A total of 217 welders were sampled for the study out of a total of 496 registered welders in Port Harcourt. The probability sampling technique was used in determining the sample population for the study. Descriptive statistics was used in the analysis of the data collected from the respondents. The findings of the study revealed that the air quality in the welders shop does not meet internationally accepted standards, the use of personal protective equipments is still not in its full state hence endangering lives of the welders and that large number of welders have suffered from catarrh, cough, Heart ache, waist pain skin rashes and breathing difficulty. The study recommended that health is wealth; therefore if welders must be in optimal health conditions, occupational based illness must be reduced. On the basis of this health checks for every worker must be done quarterly to verify the health status of every welder as to reduce their health risk. It also recommended that there is need for quarterly air quality assessment to be done to assess the air quality status of the welder's worksite and then identify generators/sources of pollutants, so as to reduce their occurrence.

https://www.lupinepublishers.com/chemistry-journal/fulltext/air-quality-in-welding-workshops-and-its-health-implication-on-welders-in-port-harcourt.ID.000138.php

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3D Printing of Pharmaceutical Drug Delivery Systems (AOICS) - Lupine Publishers

3D Printing of Pharmaceutical Drug Delivery Systems (AOICS) - Lupine Publishers

Three-dimensional printing (3DP) enables the development of diverse geometries through computer aided design using different techniques and materials for desired applications such as pharmaceutical drug delivery medicine. The FDA approval (2015) of printed-medicine opens up an unprecedented opportunity for the discovery of new compounds and technologies for the pharmaceutical industry development. This report shows some advantages, limitations, challenges and perspectives in concerning to 3DP of pharmaceutical grade formulations and polymers used for drug delivery systems. 

https://www.lupinepublishers.com/chemistry-journal/fulltext/3D-printing-of-pharmaceutical-drug-delivery-systems.ID.000109.php

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Multi-Component Synthesis of Novel Diazoles: their Characterization and Biological Evaluation (AOICS) - Lupine Publishers

Multi-Component Synthesis of Novel Diazoles: their Characterization and Biological Evaluation (AOICS) - Lupine Publishers

A new series of imidazoles were synthesized by multiple component system through condensation reaction of benzil, substituted aldehydes, substituted anilines and ammonium acetate. Glacial acetic acid was used as solvent. The bonding behavior and structure of the prepared compounds have been deduced from infra red spectroscopy, conduction method, and CHN analysis data. The synthesized imidazoles have been examined for in-vitro antibacterial properties. The results of these studies have shown that all compounds exhibited fair to major antibacterial activity against one or more bacterial strains.

https://www.lupinepublishers.com/chemistry-journal/fulltext/multi-component-synthesis-of-novel-diazoles-their-characterization-and-biological-evaluation.ID.000107.php

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